Correlation Analysis of Enverontmental Cd Exposure in Liver and Meat of Broiler Chicken
Keywords:
Broiler chicken, cadmium, feed, liver, meat, waterAbstract
Cadmium (Cd) belongs to heavy metal with high anthropogenic pollutant and non-essential to physiological funtion. Regular intake of consuming Cd leads to physiological disorders in poultry animal as well as humans as one who consume it. The aim of this study was to analyze the profile of Cd content in environmental samples (poultry feed and water) and it correlated with the degree of contamination in broiler tissues. In this study, 30 samples of feeds and water samples along with 60 samples of liver and muscle have been examined. The results showed that the feed was indicated to Cd between 0.009-0.202 mg / kg and in the water between 0.0068-0.0096 mg / l. Cd in the livers and muscles was then positively contaminated by Cd between 0.438-0.565 mg / kg and the levels was significantly different (p <0.05) among organs. A strong positive correlation was found between Cd and water levels in liver (r = 0.896). In contrast, a weaker positive correlation (r = 0.596) was found in the water and muscle. In conclusion, Cd contamination in feed and water correlated positively with the increasing amount of the cadmium level in organs.References
Abduljaleel, Salma dan Othman, MS. 2013. Toxicity of Cadmium and Lead in Gallus gallus domesticus Assesment of Body Weight amd Metal Content in Tissues after Metal Dietery Supplements. Park J. Biol. Sci. 16 (22) : 1551-1556. (Journal)
Abib RT, Peres KC, Barbosa AM, Peres TV, Bernardes A,Zimmermann LM, Quincozes-Santos A, Fiedler HD, Leal RB,Farina M, Gottfried C. 2011. Epigallocatechin-3-gallate protectsrat brain mitochondria against cadmium-induced damage. J Food Chem Toxicol 49(10):2618–2623. (Journal)
Athena, Musadad A, Sukar. 2008. Risiko kesehatan masyarakat akibat konsumsi air bersih dan hasil laut yang mengandung kadmium (cd) di kepulauan seribu. J Eko Kes 7(1):678-688. (Journal)
ATSDR (Agency for Toxic Substances and Disease Registry). 2008. Draft Toxicological Profile for Cadmium. US Department of Human and Health Services. Page 57-64. (Book)
Barbier, O., Jacquillet, G., Tauc, M., Cougnon, M. dan Poujeol P. 2005. Effect of heavy metals on, and handling by, the kidney. J Nephron Physiol. 99:105–10. (Journal)
Blagojevic, J., Jovanovic, V., Stamenkovic, G., Jojic, V., Bugarski-Stanojevic, V., Adnadevic, T. dan Vujosevic, M. 2012. Age Differences In Bioaccumulation Of Heavy Metals In Populations of The Black- Striped Fiels Mouse Apodemusagrarius (Rodentia, Mammalia). Int J Environ Res. 6(4): 1045-1052. (Journal)
Bobocea AC, Fertig ET, Pislea M, Seremet T, Katona G, Magdalena M, Doagă IO, Radu E, Horváth J. 2008. Cadmium and Soft Laser Radiation Effects on Human T Cells Viability and Death Style Choices. J Rom biophys 18:179–193.
Bridges CC, Zalups RK. 2005. Molecular and ionic mimicry and the transport of toxic metals. J Toxicol Appl Pharmacol 204:274–308. (Journal)
Dirjen PKH. 2016. Statistik Peternakan dan Kesehatan Hewan Tahun 2016. Direktorat Jenderal Peternakan dan Kesehatan Hewan, Kementerian Pertanian. Jakarta. (Book)
FerramolaML, PerezDiazMF, HonoreSM, Sanchez SS,Anton RI, Anzulovich AC, Gimenez MS. 2012. Cadmium-induced oxidative stress and histological damage in the myocardium. Effects of a soybased diet. J Toxicol Appl Pharmacol 265(3):380–389. (Journal)
Fitzgerald, PR., Peterson, J., Lue-Hing, C. 1985. Heavy Metals In Tissues Of Cattle Exposed To Sludge-Treated Pastures For Eight Years. Am J Vet Res 46 : 703-707
Flora, S. J. S. 2009. Metal Poisoning: Treatment and Management. Review Article. Al Ameen. J Med Sci 2:4-26. (Journal)
Gonzalez, D., Karlsson, L., Caballero, A., Hernandez, F., Gutierrez, A., dan Gonzalez-Iglesias. 2006. Lead and cadmium in meat and meat products consumed by the population in Tenerife Island. J Spain Food Addit Contam. 23:757–63. (Journal)
Klaassen CD, Liu J, Diwan BA. 2009. Metallothionein protection of cadmium toxicity. J Toxicol Appl Pharmacol vol. 238, pp:215–220. (Journal)
Liu J, Qu W, Kadiiska MB. 2009. Role of oxidative stress in cadmium toxicity and carcinogenesis. J Toxicol Appl Pharmacol 238:209–214. (Journal)
Mehrotra, V., V.L.V., dan Saxena, AK. 2008. Impact of Different Doses of Lead on Internal Organs of Quials. J. Environ. Biol. 29:147-149. (Journal)
Miranda, M. 2005. Effects of moderate pollution on toxic and trace metal levels in calves from a polluted area of northern spain. Journal of Environment International. 31: 543-548 . (Journal)
Mor, F., Kursun, O. dan Erdogan N. 2009. Effects of heavy metals residues on human health. J Fac Vet Med. 28(1): 59-65. (Journal)
Nangkiawa, TK., Detha, AIR. Dan Ndaong, NA. 2015. Identifikasi Kandungan Logam Berat Kadmium (Cd) Pada Sapi Potong Yang Dipelihara Di Tempat Pembuangan Akhir (Tpa) Kecamatan Alak, Kota Kupang. Jurnal kajian Veteriner. 3 (1):53-61. (Journal)
Nikic D, Stankovic A, Nikolic M, Bogdanovic D, Petrovic B. 2009. Estimated daily intake of cadmium by children living in the city of Niš, Serbia. J The Turkish of Pediatrics 51:257-263. (Journal)
Orlowski, C., Piotrowski, JK. 2003. Biological levels of cadmium and zinc in the small intestine of non-occupationally exp. (Journal)osed human subjects. J Hum Exp Toxicol. 22:57–63
Patrick, L. 2003. Toxic Metals and Antioxidants. Part II the Role of Antioxidant in Arsenic and Cadmium Toxicity – Toxic Metals part II. Alternativer Medicine Review.
Sant’ana, Moraes, R., dan Bernard, MM. 2005. Toxicity Cadmium in Japanese Quail: Evaluation of Body Weight Hepatic and Renal Function and Cellular Imune Response. J Environ Res. 99:223-227. (Journal)
Trampel, DW., Imerman, PM., Carson, TL., Kinker, JA., dan Ensley, SM. 2003. Lead contamination of chicken egg and tissue from a small farm flock. J Vet Diagn Invest. (15):418-422. (Journal)
US EPA. 2006. Integrated risk information system (IRIS). United States Environmental Protection Agency. Page 283-289. (Book)
Vargas LM, Soares MB, Izaguirry AP, Ludtke DS, Braga HC, Savegnago L, Wollenhaupt S, Brum Ddos S, Leivas FG, Santos FW . 2013. Cadmium inhibits the ovary delta-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside. J Appl Toxicol 33(7):679–684. (Journal)
Wang B, Luo Q, Shao C, Li X, Li F, Liu Y, Sun L, Li Y, Cai L. 2013. The late and persistent pathogenic effects of cadmium at very low levels on the kidney of rats. J Appl Toxicol 11(1):60–81. (Journal)
Zalups, RK. 2003. Molecular handling of cadmium in transporting epithelia. Toxicol Appl Pharmacol. 186:163–188. (Journal)
