Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) https://journal.unhas.ac.id/index.php/ica <p align="justify">Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) is a peer-reviewed research journal that is devoted to the dissemination of new and original knowledge in all branches of chemistry. The result of research and development in the fields of chemistry in both experimental and theory/ computation, chemical-based technological innovations, and chemical applications in industrial fields. The journal publishes original research articles or review articles in organic chemistry, inorganic chemistry, analytical chemistry, physical chemistry, biochemistry, and environmental chemistry. Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) is a journal published by Department of Chemistry Faculty of Mathematics and Natural Sciences, Hasanuddin University, where it was published twice in a year in June and December.</p><p align="justify">The Journal has been accredited by Akreditasi Jurnal Nasional (ARJUNA) officially Managed by Ministry of Research, Technology, and Higher Education, Republic Indonesia with Third Grade (SINTA 3) since year 2019 to 2023 according to the decree <a title="SK" href="http://arjuna.ristekdikti.go.id/files/berita/Pemberitahuan_Hasil_Akreditasi_Jurnal_Ilmiah_Periode_V_Tahun_2019.pdf" target="_blank">Number 28/E/KPT/2019</a>.</p><p><strong>p-ISSN: <strong><a title="ISSN Print" href="http://issn.pdii.lipi.go.id/issn.cgi?daftar&amp;1230708657&amp;1&amp;&amp;" target="_blank">2085-014X</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </strong></strong><strong>e-ISSN: <a title="ISSN Online" href="http://issn.pdii.lipi.go.id/issn.cgi?daftar&amp;1544263050&amp;1&amp;&amp;" target="_blank"><strong>2655-6049</strong></a></strong></p> en-US <p style="text-align: justify;">This is an open access journal which means that all contents is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.</p><p style="text-align: justify;">Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) operates a CC BY-SA 4.0 © license for journal papers. Copyright remains with the author, but Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) is licensed to publish the paper, and the author agrees to make the article available with the CC BY-SA 4.0 license. Reproduction as another journal article in whole or in part would be plagiarism. Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) reserves all rights except those granted in this copyright notice.</p> ica@unhas.ac.id (Indonesia Chimica Acta Journal (ICAJ)) arrahmanarif.10@gmail.com (Abdur Rahman Arif) Sat, 17 Sep 2022 00:00:00 +0000 OJS 3.2.1.1 http://blogs.law.harvard.edu/tech/rss 60 R The effect of titanium dioxide nanoparticle composites as an antibacterial in synthesizing polyurethane biopolymers. https://journal.unhas.ac.id/index.php/ica/article/view/24324 <p><strong>Abstract</strong>. In the health sector, the use of polyurethane (PU) as a basic material for the manufacture of medical devices also creates problems related to local and systemic infections. One of the most appropriate ways to overcome this problem is to add titanium dioxide (TiO<sub>2</sub>) nanoparticles to the urethane polymer to produce a biodegradable polymer and bacterial decontamination. In synthesizing decontaminating polyurethane bacteria, several characterization techniques were carried out, including polymer test, namely strain and stress, functional group analysis using Fourier Transform Infra-Red (FTIR), and antibacterial test. Based on the results of the FTIR test analysis, shows a change in the functional group. At wave number 1724.36 cm-1, the N-H functional group appears, this absorption is the absorption of the urethane group and TiO<sub>2</sub> is in the range of 513.07 cm-1. Mechanical properties test showed strain (28.92 - 21.88% GL) and young modulus at intervals (5,484-3,268 MPa). and the antibacterial test showed that the inhibitory power of test samples A1 and A4 with resistance diameters of 8mm and 8mm proved to be very effective in killing <em>E.Coli</em> bacteria while A1¹, A2¹, A3¹, and A4 killed could not kill <em>S. Aureus</em> bacteria inhibitors. The characterization results show that the polyurethane biopolymer can be used as a medical device with bacterial decontamination properties.</p> andibudirohmi andi rahmi Copyright (c) https://journal.unhas.ac.id/index.php/ica/article/view/24324 Nuramaniyah Taufiq1*, Sulfiani2 https://journal.unhas.ac.id/index.php/ica/article/view/23877 <p>Tuberculosis (TB) is the most common infectious disease in the world, with an estimated third of the population infected and 2.5 million people. The use of plants as traditional medicine <em>M. tuberculosis </em>is widely used as an alternative prayer, Javanese bark <em>(Lannea coromandelica) </em>contains metabolites of seconder saponins, tannins, phenolics, flavonoids, the mechanism of action of flavonoids and some phenolic compounds as antituberculosis is to destroy the cytoplasmic membrane. This study aimed to determine the activity of Ethanol Extract and N-Hexane Bark Trunk (<em>Lannea Coromandelica</em>) Against the Growth of <em>Mycobacterium Tuberculosis. </em>The method used <em>Mycobacterium tuberculosis, </em>Loweinstein Jensen (LJ) medium, and ethanol extract at a concentration of 0.1 g, 0.2 g, and 0.3 g at week 6 showing sensitive results and in N-Hexane solvents at concentrations of 0.1 g, 0.2 g, 0.3 g at week 6 showed sensitive results</p> Nuramaniyah Taufiq Copyright (c) https://journal.unhas.ac.id/index.php/ica/article/view/23877 BIODEGRADATION TEST Of Bacillus subtilis BACTERIA ISOLATE AGAINST Zn METAL FROM POBOYA PALU GOLD MINING LAND https://journal.unhas.ac.id/index.php/ica/article/view/23544 <p>The gold mining industry in Poboya Palu which is growing rapidly has an environmental impact on the waste produced. The purpose of this study was to analyze the zinc metal content in the gold mining waste of Poboya Palu, and to determine the final zinc metal content in the biodegradation product. Soil samples were obtained from the Poboya Gold Mine in Palu. This research was carried out by inoculating bacteria into Luria Broth (LB) liquid medium which had been enriched with ZnSO<sub>4</sub>7H<sub>2</sub>O&nbsp; 0 ppm, 5 ppm, 10 ppm, 15 ppm, and 20 ppm, respectively. Then it was incubated for ± 48 hours and the Optical Density (OD) value was measured at a wavelength of 660 nm to determine the level of bacterial density on the spectrophotometer. The zinc content of the Poboya Gold Mine obtained was 39,7473 mg/kg. Growth optimization occurred during the 24 hour incubation period for concentrations of 5 ppm, 10 ppm and 15 ppm. The isolate of Bacillus subtilis able to reduce zinc metal levels with the results of a decrease for each concentration of 5 ppm by 50%, 10 ppm by 41% ppm and 15 ppm by 38%.</p> Fitriyana Copyright (c) https://journal.unhas.ac.id/index.php/ica/article/view/23544 Microwave Assisted Hydrodistillation Essential Oil from Lime Peel Waste As Aromatherapy Candles https://journal.unhas.ac.id/index.php/ica/article/view/22562 <p>Flavonoids are the largest group of polyphenol compounds that can work as antioxidants, and also as antibacterials by denatured bacterial cell proteins and damaging bacterial cells. One of the sources of essential oils is orange peel, in everyday life, citrus fruits are generally only used part of the flesh of the fruit for consumption purposes. The distillation method is used to obtain essential oils, using a <em>microwave</em> can be an alternative to conventional distillation techniques so that it is more effective and efficient. Microwave<em> Assisted Hydrodistillation</em> (MAHD) method is more energy efficient, environmentally friendly, fast, safe, and cost-effective than the extraction process using other methods. This study aims to determine the <em>Microwave Assisted Hydrodistillation</em> method on the quantity and quality of essential oils <em>(essential oils)</em> produced from lime peels through laboratory tests according to SNI standards, to determine the processing of lime peel waste into aromatherapy candles that function for health. This study used the Microwave assisted Hydrodistillation method with a ratio of sample mass and aquadest solvent (1: 1). The resulting essential oil is analyzed using the GC-MS method. Based on the results of the GC-MS test, essential oil from lime peel obtained the highest % of the area, namely limonene compounds by 98% at a retention time of 6,045.</p> Mariaulfa Mustam, Hijrah Amaliah Azis, Nur afdalianah Copyright (c) https://journal.unhas.ac.id/index.php/ica/article/view/22562 Extraction and Characterization of Chitosan from Vannamei Shrimp Shell Waste (Litopenaeus vannamei) https://journal.unhas.ac.id/index.php/ica/article/view/22559 <p>Shrimp is one of the biggest commodities in the Pacitan coast area that was taken its meat to be processed into many food products. This could be due to the accumulation of shrimp shell waste abundantly and has no selling value. The conversion of shrimp shell waste into chitosan is the one breakthrough to increase the value of shrimp shell waste. The objective of this research is to convert shrimp shell waste into chitosan and characterized the quality of chitosan including the deacetylation degree, crystallinity, and morphology. This research has successfully isolated chitosan extracted from vannamei’s shrimp shell waste (<em>Litopenaeus vannamei</em>) obtained from the Sudimoro coast, Pacitan, Indonesia. Chitosan was isolated through three steps of reaction including deproteination, demineralization, and deacetylation. The chitosan produced had a deacetylation degree of 85.69% and the total shrinkage from the raw material is at 84%. The synthesized chitosan also showed a decrease in its crystallinity and had flake-type morphology.</p> <p><strong>Keywords: </strong>Chitosan; Chitin; Shrimp shell; <em>Litopenaeus vannamei</em>; Pacitan</p> Lukman Atmaja, Mardi Santoso, Djoko Hartanto, Arif Priyangga, Rifdah Adya Salsabila, Anggita Ningtyas Copyright (c) https://journal.unhas.ac.id/index.php/ica/article/view/22559