Cytotoxic Activity of Bioactve Compounds from Hydroid Aglophenia cupressina Lamoureoux against Hela Tumor Cells
Keywords:
Bioactive compounds, Cytotoxic, Hela tumor cells, HydroidAbstract
Hydroids are marine invertebrates living on sponges, which belong to the phylum Coelenterata. They also contain several chemical compounds, including alkaloids, steroids, terpenoids, and histamine, which can be used as medicinal raw materials, such as antimicrobials and anticancer. Therefore, this study aimed to assess the working mechanism of active compounds obtained from the extract and the fraction of Hydroid Aglaophenia cupressina Lamoureoux against Hela ttumor cell line, as a solvent used n-hexane. The cytotoxic activity was carried out by using MTT method. The results showed both extract and fraction activities against Hela tumor cells. They were also categorized as moderate cytotoxic activity based on the IC50 values of the extract and fraction, namely 0.31726 µg/mL and 0.32712 µg/mL, respectively.
Downloads
Published
Issue
Section
License
Copyright Notice
This is an open access journal which means that all contents is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, will not be published elsewhere in the same form, in English or in any other language, without the written consent of the Publisher. An article based on a section from a completed graduate dissertation may be published in International Journal of Applied Biology, but only if this is allowed by author's(s') university rules. The Editors reserve the right to edit or otherwise alter all contributions, but authors will receive proofs for approval before publication.
International Journal of Applied Biology operates a CC-BY 4.0 © license for journal papers. Copyright remains with the author, but International Journal of Applied Biology is licensed to publish the paper, and the author agrees to make the article available with the CC-BY 4.0 license. Reproduction as another journal article in whole or in part would be plagiarism.
