HISTOLOGI LIVER BURUNG PUYUH DENGAN PEMBERIAN MINYAK ATSIRI BAWANG PUTIH (Liver Histologic of Quail with Administeration of Garlic Volatile Oil)
DOI:
https://doi.org/10.20956/jitp.v8i1.8329Keywords:
Volatile oil, histological, liver, quailAbstract
Sixty-four of female quails, twenty-two weeks old, were used in the current study to evaluate the potential of volatile oil from garlic extract in improving the histological liver of the quails. Volatile oil isolated from garlic by using destilated technique. This study was designed according to completely randomized design, consisted of four treatment groups and six replications. Each treatment group consisted of 16 quails, with supplemental volatile oil (VO) by orally, as follow L0=without of VO; L1= VO of 75 mL; L2= VO of 100 mL and L3= VO of 125 mL. Liver tissue samples were collected using a fixative solution and the liver samples were used to determine the liver histological parameters (necrosis, apoptosis, fat degeneration, hydropic degeneration, acute inflammation, hemorrhagic) by a Mallory-asan technique dan binocular microscope. The current study showed that overall results indicated a significant treatment effect (P<0,05) for the liver histological condition. In conclusion, VO resulted in supplemented levels that significantly raised protein and lipid anabolic and induced hormone signal related growth liver tissueDownloads
References
Adriani, L. Abun dan A. Mushawwir. 2015. Effect of dietary supplementation of Jengkol (Pithecellobium jiringa) skin extract on blood biochemistry and gut flora of broiler chicken. Int. J. Poult. Sci., 14(2): 407-410.
Ansar, S., M. Iqbal and N. Aljameil. 2014. Diallyl sulfide, a component of garlic, abrogates ferric nitrilotriacetate-induced oxidative stress and renal damage in rats. Human and Experimental Toxicology, 33(4): 1209-1216.
Antosiewicz, S., H. A. Anna, W.M. Stanley and V.S. Shivendra. 2016. C-jun NH2-terminal kinase signaling axis regulates diallyl trisulfide-induce generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells. Cancer Research, 66(9): 5379-5386.
Arya A, M.M. Al-Obaidi, N. Shahid, M.I. Bin Noordin, C.Y. Looi, W.F. Wong, S.L. Khaing and M.R. Mustafa. 2014. Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study. Food Chem. Toxicol., 71 (3):183-96.
Bertaggia, E., G. Scabia, S. Dalise, F. Lo Verso, F. Santini, P. Vitti, C. Chisari, M. Sandri and M. Maffei. 2014. Haptoglobin is required to prevent oxidative stress and muscle atrophy. PLoS One, 9: e100745.
Blok, E. 1985. The chemistry of garlic and onion. Sci. American, 252 (1): 115-119.
Borek, C. 2001. Antioxidant health effects of aged garlic extract. J. Nutr., 131(3): 1010S-1015S.
Bose, C., J. Guo, L. Zimniak, S.K. Sricastava, S.P. Singh, P. Zimniak and S. C. Singh. 2002. A critical role of allyl groups and disulfide chain in the induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, naturally according to the chemopreventive agent in garlic. Carcinogenesis, 23 (5):1661-1665.
Bose, C., J. Guo, L. Zimniak, S.K. Sricastava, S.P. Singh, P. Zimniak and S. C. Singh. 2012. Critical role of allyl groups and disulfide chain in the induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally according chemopreventive agent in garlic. Carcinogenesis, 23 (8): 1661-1665.
Burdick, N. C., J.A. Carroll R. Randel, S. Willard, R.Vann, C.C. Chase, S. Lawhon, L. Hulbert and J.T. Welsh. 2011. Influence of temperament and transportation on physiological and endocrinological parameters in bulls. Livestock Sci., 39(3): 213–221.
Chatterjee, N., S. Das, D. Bose, S. Banerjee, T. Jha and K.D. Saha. 2015. Leishmanial lipid affords protection against oxidative stress-induced hepatic injury by regulating inflammatory mediators and confining apoptosis progress. Toxicol. Lett., 232(3): 499-512.
Cortes-Coronado, R.F., S. Gomez-Rosales M.D.L. Angeles, M.T. Casaubon-Huguenin and T. Sorensen-Dalgaard. 2017. Influence of a yeast fermented product on the serum levels of the mannan-binding lectin and the antibodies against the Newcastle disease virus in Ross broilers. J. Appl. Poult. Res., 26(5): 38-49.
Damaziak, K., J. Riedel, D. Gozdowski, J. Niemiec, A. Siennicka and D. Rog. 2017. Productive performance and egg quality of laying hens fed diets supplemented with garlic and onion extracts. J. Appl. Poult. Res., 26(7): 337–349.
Eyng, C., A.E. Murakami, T.C. Santos, T.G.V. Silveira, R.B. Pedrosa and D.A.L. Lourenco. 2015. Immune responses in broiler chicks fed propolis extraction residue-supplemented diets. Asian-Australas. J. Anim. Sci., 28(1): 135-142.
Gomez, K.A. dan A.A. Gomez. 1995. Prosedur Statistika untuk Penelitian Pertanian. Edisi Kedua. Penerbit Universitas Indonesia, Jakarta.
Kim Y. J., S.K. Jin and H.S. Yang. 2009. Effect of dietary garlic bulb and husk on the physicochemical properties of chicken meat. Poult. Sci., 88(4): 398-405.
Korivi M, C.W. Hou, C.Y. Huang, S.D. Lee, M.F. Hsu M.F, S.H. Yu, C.Y. Chen, Y.Y. Liu and C.H. Kuo. 2012. Ginsenoside-Rg1 protects the liver against exhaustive exercise induced oxidative stress in rats. Evid Based Complement Alternat Med., 2012: 932165.
Kumar, S.N., B. Bastia, A.G. Telang, K.P. Singh, R. Singh and A.K. Jain. 2015. Combined toxicity of endosulfan and ochratoxin-A in rats: histopathological changes. J. Histol. Histopathol., 2(9): 22-27.
Lai, Y.S., W.C. Chen, C.T. Ho, K.H. Lu, S.H. Lin, H.C. Tseng, S.Y. Lin and L.Y. Sheen. 2014. Garlic essential oil protects against obesity-triggered nonalcoholic fatty liver disease through modulation of lipid metabolism and oxidative stress. J. Agric. Food. Chem., 62(1): 5897-5906.
Lee D.H., S.R. Lim, S.S. Ra and J.D. Kim. 2014. Effects of dietary garlic powder on growth, feed utilization and whole-body composition change in fingerling sterlet sturgeon, Acipenser ruthenus. Asian-Autralas. J. Anim. Sci., 27(5): 1419-1429.
Liu, C.M., Y.L. Zheng, J. Lu, Z.F. Zhang, S.H. Fan, D.M. Wu and J.Q. Ma. 2010. Quercetin protects rat liver against lead-induced oxidative stress and apoptosis. Environ. Toxicol Pharmacol., 29(7): 158-166.
McManaman, J.L., E.S. Bales, D.J. Orlicky, M. Jackman, P.S. MacLean, S. Cain, A.E. Crunk, A. Mansur, C.E. Graham, T.A. Bowman and A.S. Greenberg. 2013. Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J. Lipid Res., 54(4): 1346-1359.
Mohanty, S.R., S.K. Sahoo, L.K. Babu, C.R. Pradhan, B. Panigrahi and S.K. Joshi. 2015. Effect of feeding different levels of protein on egg weight, egg quality, fertility, hatchability and fatty acid profile of eggs in Khaki Campbell duck during laying period. Indian Vet. J., 92(4): 25-30.
Murray, R.K., D.A. Bender, K.M. Botham, P.J. Kennelly, V.W. Rodwell and P.A. Weil. 2012. Biokimia Harper, Edisi 29. EGC Penerbit Buku Kedokteran, Jakarta.
Mushawwir, A., U.H. Tanuwiria, K.A. Kamil, L. Adriani and R. Wiradimadja. 2017. Effects of volatile oil of garlic on feed utilization, blood biochemistry and performance of heat-stressed japanese quail. Asian J. Poult. Sci., 11 (2): 83-89.
Mushawwir, A., U.H. Tanuwiria, K.A. Kurnia, L. Adriani, R. Wiradimadja and N. Suwarno. 2018. Evaluation of haematological responses and blood biochemical parameters of heat-stressed broilers with dietary supplementation of Javanese Ginger Powder (Curcuma xanthorrhiza) and Garlic Extract (Allium sativum). Int. J. Poult. Sci., 17(3): 452-458.
Mushawwir, A., Y.K. Yong, L. Adriani, E. Hernawan and K.A. Kamil. 2010. The Fluctuation Effect of Atmospheric Ammonia (NH3) Exposure and Microclimate on Hereford Bulls Hematochemical. J. Indon. Tropical Anim. Agric., 35 (5): 232-238.
Mushawwir, A., L. Adriani and K.A. Kamil. 2011. Prediction models for olfactory metabolic and sows’ rnareticulocyt (Rnart) by measurement of atmospheric ammonia exposure and microclimate level. J. Indon. Tropical. Anim. Agric.., 36(1): 14-20.
Nelson, D.L. and M.M. Cox. 2008. Lehninger Principles of Biochemistry. W.H. Freeman and Company, New York, USA.
Peinado M. J., R. Ruiz and A. Echavarri. 2012. Garlic derivative propyl propane thiosulfonate is effective against broiler enteropathogens in vivo. Poult. Sci., 91(1): 2148-2157.
Pickler , L., C.B. Breno, Beirão , M.H. Ricardo, F.D. Jean, C.L. Mariana, F.C. Luiz and E. Santin. 2013. Effect of sanguinarine in drinking water on Salmonella control and the expression of immune cells in peripheral blood and intestinal mucosa of broilers. J. Appl. Poult. Res., 22(3): 430–438.
Rachmawati, S. 2005. Aflatoksin dalam pakan ternak di Indonesia: persyaratakan kadar dan pengembangan teknik deteksinya. Wartazoa, 15(3): 26-37.
Robert, V., B. Mouille, C. Mayeur, M. Michaud and F. Blachier. 2011. Effects of the galic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cell: evidence of sensitive and resistant sub-population. Carcinogenesis, 22(8): 1155-1161.
Sirovina D, N. Orsolic, M.Z. Koncic, G. Kovacevic, V. Benkovic and G. Gregorovic. 2013. Quercetin vs chrysin: effect on liver histopathology in diabetic mice. Hum. Exp. Toxicol., 32(7): 1058-1066.
Soisuwan, K. and N. Chauychuwong. 2013. Effects of phytogenic feed additive with reduced dietary metabolizable energy and digestible essential amino acids on carcass yields and meat quality of pekin ducks. J. Appl. Sci. Res., 9(5): 6099–6102.
Weng, D., Y. Lu, Y. Wei, Y. Liu and P. Shen. 2007. The role of ROS in microcystin-LR-induced hepatocyte apoptosis and liver injury in mice. Toxicology, 232(5): 15-23.
Yang, S. C., K.C. Saranjit, H. Jun-Yan, and J.S. Theresa. 2011. Mechanism of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and relate compounds from garlic. J. Nutr., 131(3): 1041S-1045S.
Yarrus, L. P., R.S. Settivari, N.K.S. Gowda, E. Antoniou, D.R. Ledoux and G.E. Rottinghaus. 2009. Effects of turmeric (Curcuma longa) on the expression of hepatic genes associated with biotransformation, antioxidant, and immune systems in broiler chicks fed aflatoxin. Poult. Sci., 88(3): 2620-2627.
