Antioxidant Activity from synthesis product of Hydoxycinamic Acid Derivative. Antioxidant Activity from synthesis product of Hydoxycinamic Acid Derivative.
Article Sidebar
Abstract
Hydroxycinamic acid derivatives have potential as antioxidants. The synthesis of hydroxycinamic acid derivatives from p-coumaric acid with hexylamine yielded 4-(3-hexylamine-3-oxopropenyl) phenyl acetate compounds. Synthesis is carried out through the acetylation, chlorination, and amidation reaction stages. Amidation products were characterized by TLC test, melting point determination, FT-IR spectroscopy. The antioxidant activity was tested using 1,1-diphenyl picrylhydrazyl (DPPH). The results showed that the compound obtained was a white crystalline solid (yield 15.59%, melting point 104 - 106 °C). Compound 4 only shows very weak antioxidant activity with an IC50 value of 11453.03 μg / mL%. Thus compound 4 has no potential as an antioxidant.
Full text article
Authors
Copyright (c) 2021 Ni Kadek Ayu Novia
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This is an open access journal which means that all contents is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author.
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) operates a CC BY-SA 4.0 © license for journal papers. Copyright remains with the author, but Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) is licensed to publish the paper, and the author agrees to make the article available with the CC BY-SA 4.0 license. Reproduction as another journal article in whole or in part would be plagiarism. Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) reserves all rights except those granted in this copyright notice.