EFEK PROTEIN SEMPURNA DAN TIDAK SEMPURNA TERHADAP BERAT BADAN DAN ALBUMIN TIKUS

Authors

  • hermawati Hermawati
  • Abdul Salam
  • Sabaria Manti Battung

Abstract

Introduction: Protein is the trigger for the occurrence of obesity and changes in albumin levels
in weight gain. Obesity is one of the most serious public health challenges in the 21st century. Objektive:
This study aimed to determine the effects of high-protein complete and uncomplete diet to weight gain
and albumin levels in wistar rats. Methods: The samples used 15 wistas rats which were divided
randomly into 3 groups, each consisting of 5 tails weighing 150-200 g and in healthy condition.
Standard AD 2 feed was given to the control group, intervention feed given to complete protein and
soybean intervention feed protein group was uncomplete. The study was conducted for 6 weeks, 2 weeks
of adaptation and 4 weeks of intervention. The research method used a true experiment with a
randomized control group pretest-posttest desigen. The data collected consisted of weighing the body
and measuring the rat albumin level which was carried out 2 times before the intervention day 0 and
after the intervention of the 28th day. Data analysis used One Way ANOVA statistical test followed by
Post Hoc Tukey and Paired Sample Test was accepted if p <0.05. Results: The results of measurements
of weight gain obtained before the intervention were not significant with p = 0.790 and measurements
after intervention obtained significant results with a value of p = 0.014, as well as examination of
insignificant albumin levels before intervention with p = 0.251 and significant on examination after the
intervention with a value of p = 0.003. Conclusion: It It can be concluded as an intervention after
weight gain and albumin levels.

References

Budiarso F, Novi, Ronald O, dan Winston P. 2018. IPTEKS Penyuluhan Tentang Obesitas Dan

Pengukuran Indeks Massa Tubuh Pada Masyarakat Kelurahan Malendeng Kecamatan Paal 2 Kota

Manado. Jurnal Kedokteran dan Terapik. Volume 6. Nomor 2. Fakultas Kedokteran Universitas

Sam Ratulangi Manado.

WHO. World Health Organization. 2018. 'Obesity and Overweight'. [cited 2018 Oct 18]. Available

fromhttp://www.who.int/mediacentre/factsheets/fs311/en.

Ellulu M, Yehia Abed, Asmah Rahmat, Yazan Ranneh, and Faisal Ali. 2014. Epidemiology of

Obesity in Developing Countries: Challenges and

Almatsier S. 2009. Prinsip-prinsip dasar ilmu gizi. Jakarta: Gramedia Pustaka Utama

French W, Sami D, Stephanie A. Shouse, Hexirui Wu , Aubree H, Sun-Ok Lee, Xuan Gu and Jamie

I. Baum. 2017. A High-Protein Diet Reduces Weight

Kurnia P. 2010. Efek Fortifikasi Fe dan Zn pada biskuit yang diolah dari kombinasi tempe dan

bekatul untuk meningkatkan kadar albumin anak balita kurang gizi dan anemia. J Ekplanasi 5(2).

Hidayat M, Soeng, S., Wahyudianingsih, R., Ladi JE., Krisetya, YA., dan Elviora, V., 2015. Ekstrak

Kedelai Detam 1, Daun Jati Belanda Serta Kombinasinya Terhadap Berat Badan dan

Histopatologis Hepar Tikus Wistar. JKKI, 6(4), p. 167-178.

Farnsworth, E.; Luscombe, N.D.; Noakes, M.; Wittert, G.; Argyiou, E.; Clifton, P.M. Effect of a

high-protein, energy-restricted

diet

on

body

composition,

glycemic control,

and

lipid

concentrations in overweight and obese hyperinsulinemic men and women. Am. J. Clin. Nutr. 2003,

, 31–39. [PubMed]

Mitchell, CJ, McGregor, RA, Souza, RFD, Thorstensen, EB. Markworth, JF, Fanning, AC, Poppitt,

SD, Cameron-Smith, D. Consumption of Milk Protein or Whey Protein Results in a Similar Increase

in Muscle Protein Synthesis in Middle Aged Men. Nutrients. 2015;7(10):8685-8699.

Winarsi. 2010. Protein Kedelai & Kecambah Manfaat Bagi Kesehatan. Penerbit Kanisius:

Yogyakarta.

Stump SE. Nutrition And Diagnosos-Reklated Care. USA: 17. Liponcott WW Philadhelpia; 2008.

Prastowo A, Wiryatum Lestariana , Siti Nurdjhanah, dan Retno Sutomo. 2016. Efek Pemberian

Ekstrak Putih Telur Terhadap Peningkatan Kadar Albumin dan IL-6 Pada Pasien Tuberkolosisi

Dengan Hipoalbumin. Jurnal kesehatan. Vol 1. No 1, pp 10-18.

Mercer T AE, Johnson CA, Yarasheski KE, Carnell NS, Campbell WW. Nutrient Ingestion, Protein

Intake, and Sex, but Not Age, Affect the Albumin Synthesis Rate in Humans. American Society for

Nutrition. 2007;1734-40.

Harna, Clara M.Kusharto, dan Katrin Roosita. 2017. Intervensi Susu Tinggi Protein Terhadap

Tingkat Konsumsi Zat Gizi Makro dan Status Gizi Pada Kelompok Usia Dewasa. Jurnal MKMI.

Institusi Pertania Bogor. Vol 13. No 4, pp. 355-361.

Farzana FD, Ahmed S, Ferdous F, Venderlee L, Khan SH, Roy AK, et al. Biochemical and Dietary

Indicators among Vegetarians and Non-Vegetarians: Finding from A Cross Sectional Study in

Rural Bangladesh. International Journal of Nutrition and Food Sciences. 2013;2:130-6.

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Published

2019-08-20