Perbandingan Kadar High Density Lipoprotein dan Indeks Massa Tubuh antara Akseptor KB Pil Kombinasi dengan Depo Medroksiprogesteron
Abstract
More than six million women worldwide use contraceptive injection and the popular contraceptive methodused is contraceptive pill. This is due to one of the side effects of combination pill contraception is to increasetriglyceride levels, total cholesterol and changes in carbohydrate metabolism while the side effects of DepotMedroxyprogesterone Acetate are irregular menstruation/amenorrhea, changes in body weight and lipid changes.This research is an observational with cross sectional comparative approach to 36 combination pill acceptorand 36 Depot Medroxyprogesterone Acetate acceptor. This study was conducted ini the area of Andalas andLubuk Buaya Health Center. The sampling method used in this research was simple random sampling method.The analysis was used T-Independent test and chi square test. The results showed that High Density Lipoproteinleves Depot Medroxyprogesterone Acetate (63,97±12,75 mg/dl) vs combined contraceptive pill (60,06±15,57 mg/dl), p=0,25 and Body Mass Index levels of overweight combined contraceptive pill acceptor higher than DepotMedroxyprogesterone Acetate (p=0,08). Results of this study concluded was that there were no significantdifferences in the levels of High Density Lipoprotein and Body Mass Index between combined contraceptive pilland Depot Medroxyprogesterone Acetate acceptor
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2. Fraser, DM (eds.). Myles Textbook for Midwives (Edisi 14). Jakarta : EGC; 2011.
3. Manuaba, IAC. Manuaba, IBGF. Manuaba IBG. Ilmu Kebidanan, Penyakit Kandungan & KB untuk Pendidik Bidan. Jakarta : EGC; 2010.
4. Cunningham G., Leveno R.J., Bloom S.I. et al. Obstetri Williams (Terjemahaan : Pendit, BU. Dimanti, A. Chairunnisa. Mahanani, DA. Yesdelita, N. Dwijayanthi, L. et al). Jakarta : EGC; 2014.
5. Glasier, Anna. Keluarga Berencana dan Ke sehatan Reproduksi (Edisi 4). Dalam : Kontrasepsi Oral Kombinasi, Guillebaud, Jhon, (Terjemahaan : Brahm U Pendit). Jakarta : EGC; 2012.
6. Mayes, PA, Khathleen MB. Metabolisme Asilgliserol dan Sfingolipid ; Pengangkutan & Penyimpanan Lipid ; Pengangkutan dan Ekskresi Kolesterol. Dalam : Biokimia Harper (Edisi 27), Alih Bahasa Brahm U Pendit, Jakarta : EGC; 2012.
7. Adam J. Buku Ajar Ilmu Penyakit Dalam (Edisi IV Jilid III). Dalam : Hormon Steroid. Jakarta : Departemen Ilmu Penyakit Dalam Fakultas Kedoteran UI Editor : Sudoyo AW, et all; 2006.
8. Ulla M. Anttila, M. Liukko, KM. Rantala, Maija-Liisa. Rautianinem, H. Werner F. Sommer and Mamaers, E. Effects of a Monophase Combined Oral Contraceptive Containing Nomegesteral and Ethininglesteradiol on
Haemotasis Lipids and Carbohydrate Metabolism. The European Journal of Contraception and Reproductive Health Care. 2011;16:444-457.
9. Jung, UJ dan Chio, MS.Obesity and Its Metabolic Complication the Role of Adipokines and the Relationship between Obesity, Inflamation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease. International Journal of Moleculer Sciences. 2014;15:6184-6223. DOI: 10.3390/ijms15046184.
10. Mohammad, NS. Nazli, R. Khan, MA. Akhtar, T. Ahmad, J. Zafar, Z. Effect of Combined Oral Contraceptive Pills on Lipid Profile, Blood Pressure and Body Mass Index in Women Of Child Bearing Age. KMUJ. 2013;5(1):22-26.
11. Yen-chi L, LE. Rahma, M dan Berenson, A.B. Early Weight Gain Predicting Later Weight Gain Among Depot Medroxyprogesteron Acetat User’s. National Instituties of Health Public Acces. 2009;114(2):279-284. DOI :10.1097/AOG. 0b013e3181af68b2 .
12. Lizarelli MP, Martins PW, VieiraSC, Soares MG, Franceschini AS, Ferriani AR, Patta CM. Both a Combined Oral Contraceptive and Depot Medroxyprogesterone Acetate Impair Endothelial Function in Young Women. J. Contraception. 2009;79:35-40.
13. Okeke, CU. Braide, SA. Okolonkwo, BN. Okafor, R. Eneh2, PC. Adegoke, A. et al. Comparative Effect of Injectable and Hormonal Contraceptives on Lipid Profil. European Journal Of Cardiovascular Medicine. 2011; 2(1):20-21. DOI : 10.5083/ejcm.20424884.64
14. Fekadie, M. Seifu, D. Kumpi, S. Kokeb, A. Effect of Depo-Medroxyprogesteron Acetate (DMPA) on Lipid Metabolism. International Journal of Reaserch in Biotechnology and Biochemistry. 2016;6(1):6-11.
15. Al-Youzbaki, WB. C-Reactive Protein and Lipid Profile Among Depo Medroxyprogesteron Acetat Injection Users. Annals of the College of Medicine. 2011;37(1&2):48-56.
16. Affandi, B. Adriaansz, GA. Gunardi, ER. Koesno, Harni. Buku Panduan Praktis Pelayanan Kontrasepsi (Edisi 3). Jakarta : PT. Bina Pustaka Sarwono Prawirohardjo; 2014.
17. Rashid, Shirya and Genest, Jacques. Effect of Obesity on High Density Lipoprotein Metabolism. Obesity. 2007;15(12):2875-2888.
18. Zhoun, G. Wu, Jiang. Tang, Jing. Wang, Jia-Ji. Lu, Chu-Hong and Wang, Pei-Xi. Beneficial Effect of Higher Dietary Fiber Intake of Plasma HDL-C and TC/HDL-C Ration Among Chinese Rural-to-Urban Migrant Workers. International Journal of Envirumental Research and Public Health. 2015;12:4726-4738. DOI :10.3390/ijerph120504726.
19. Khon, EJ. Lopez, MP. Simons, RH. Weight and Body Mass Index Among Female Contraceptive Clients. Elseiver. 2015;91:470-473. DOI.org/10.1016/j.contraception.
20. Bonny AE, Secic M, and Cromer BA. A Longitudinal Comparison of Body Composition Changes in Adolescent Girls Receiving Hormonal Contraception. J Adolesc Health. 2009;45(4):423–425. DOI:10.1016/j. jadohealth.2009.04.009.
Authors
Sitinjak, H. L., Rita, R. S., & ., Y. . (2019). Perbandingan Kadar High Density Lipoprotein dan Indeks Massa Tubuh antara Akseptor KB Pil Kombinasi dengan Depo Medroksiprogesteron. Media Kesehatan Masyarakat Indonesia, 15(1), 28-34. https://doi.org/10.30597/mkmi.v15i1.5520
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