Antifeedant Activity of Benzopyrans from Melicope latifolia

Mulyadi Tanjung Bio
Article History

Submited : June 20, 2020
Published : December 14, 2020

Two benzopyrans, evodionol (1), and evodion (2) were isolated from the stem bark of Melicope latifolia. The structure of both compounds was identified based on 1D and 2D NMR, UV, and IR spectroscopy. Antifeedant activity of compounds 1-2, and ethyl acetate extract, showing inhibition value of 28.9; 31.3, and 46.8%, respectively, which were categorized as moderate.

References

  1. Chandramu, C., Manohar, R.D., Krupadanam, .D. G., Dashayantha, R.V. 2003, Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L., Phytoter. Res., 17: 129-134.
  2. Chen, I. S., Chen, H. F., Cheng, M. J., Chang, Y. L., Teng, C.M., Tsutomu, I., Tsai, I.L. 2001, Quinoline alkaloids and other constituents of Melicope semecarpifolia with antiplatelet aggregation activity, J. Nat. Prod, 64 (9): 1143-1147.
  3. Hartley, T.G. 2001, Taxonomy and biogeo-graphy of Evodia and Melicope (Rutaceae), Allertonia, 8(1): 1–328.
  4. Kamperdick, C., Van, N.H., Sung, T., Adam, G. 1999, Bisquinolinone alkaloids from Melicope ptelefolia,” Phytochem., 50(1): 177-181.
  5. Kamperdick, C., Van, N.H., Sung, T., Adam, G., 1997, Benzopyrans from Melicope ptelefolia leaves,” Phytochem., 45(5): 1049-1056.
  6. Kassim, N.K., Rahmani, M., Ismail, A., Sukari, M.A., Ee, G.C.L., Nasir, N.M., Awang, K., 2013, Antioxidant activity-guided separation of coumarins and lignan from Melicope glabra (Rutaceae), Food. Chem., 139: 87-92.
  7. Nakashima, K., Oyama, M., Ito, T. , Witono, J.R., Darnaedi, D., Tanaka, T., Murata, T., Iinuma, M., 2011, Melicodenines A and B, novel Diels-Alder type adduct isolated from Melicope denhamii, Tetrahedron Lett, 52:4694-4696
  8. Saputri, R.D., Tjahjandarie. T.S., Tanjung, M, 2019, Alkaloid furokuinolin dan asam sinamat ter-O-geranilasi dari Melicope hookeri T.G. Hartley, J Sains & Kesehatan, 2: 1-7.
  9. Saputri, R.D., Tjahjandarie. T.S., Tanjung, M, 2018, Meliglabrin, a new flavonol derivative from the leaves of Melicope glabra (Blume) T.G. Hartley, Nat Prod Sci., 24: 155-158.
  10. Saputri, R.D., Tjahjandarie. T.S., Tanjung, M, 2018, Alkaloid kuinolin dari Melicope denhamii dan uji aktivitas antikankernya, J Sains & Kesehatan, 1: 505-509.
  11. Tanjung, M, Saputri, R.D., Wahjoedi, R.A., Tjahjandarie, T.S., 2017, 4-Methoxy-3-(3-methylbut-2-en-1-yl)-7-((3-methylbut-2-en-1-yl)oxy) quinolin-2(1H)-one from Melicope moluccana T.G. Hartley, Molbank, 1-5, https://www.mdpi.com/1422-8599/2017/2/M939.
  12. Tjahjandarie, T.S., Tanjung, M, Saputri, R.D., 2018, Melimoluccanin, A new isoprenylated quinolone alkaloid from the leaves of Melicope moluccana TG Hartley, Journal of Physics: Conference Series, 1095(1): 012042.

Downloads

Download data is not yet available.
Fulltext