Eksplorasi Metabolit Sekunder dari Spons di Wilayah Sulawesi Selatan dan Uji Bioaktivitasnya terhadap Artemia salina
DOI:
https://doi.org/10.20956/ica.v2i2.2465Abstract
Abstract. Explorations of secunder metabolic, especially non active fraction of Clathria reinwardtii, of spons from South Sulawesi have been done. Bioactivity test against Artemia salina was carried out with Brine Shrimp Lethality Test method. Separation techniques contain of extraction, fractionation, and purification. Qualitative tests and structure elucidation on the compound obtained was based on the physical and spectroscopic data UV, IR and NMR. Two compounds which are isolated from Clathria reinwardtii are suggested as fenolic compound and steroid group i.e. β-sitosterol.Keywords : β-sitosterol, Artemia salina Leach, Clathria reinwardtii, fenolic.
References
Anonim. 2006. Mencari Obat Mujarab Laut, (Online), (http:www. Forek. or. id, diakses 18 Februari 2007).
Charan, R.D., McKee, T.C., and Boyd, M.R., (2001), J. Nat. Prod, 64, 661-663.
Noor, A. 2007. Riset Kelautan Berorientasi Terapan: Keperluan Mendesak Bagi Kawasan Timur Indonesia. Kongres Ilmu Pengetahuan Wilayah untuk Kawasan Timur Indonesia. Pusat Kegiatan Penelitian Unhas. Makassar.
Sakai, R., Higa, T., and Jefoord, C. (1992), Manzamin A, A novel Antitumor Alkaloid from a sponge, J. Am. Chem. Soc., 11 (1), 8925-8927.
Sapar, A., A. S. Kumanireng, N. de Voogd, Alfian N, 2004. Isolasi dan Penentuan Struktur Metabolit Sekunder Aktif Dari Spons Biemma Triraphis Asal Pulau Kapodasang (Kepulauan Spermonde). Marina Chimica Acta. 6.1.
Sardjoko. 1996. Hubungan Kuantitatif Struktur dan Aktivitas, Rancangan Rasional dalam Pengembangan Senyawa Bioaktif. Makalah disajikan pada Seminar Perspektif Baru dalam Drug Discovery, Ujung Pandang.
Satari, R., 2003. Produk Alam Laut sebagai Lead Compaund untuk Farmasi dan Pertanian. Makalah disajikan pada Seminar Nasional Perspektif Baru dalam Drug Discovery, Makassar 26 Oktober 2003.
Suryati, E., Rosmiati, Parenrengi, A. 2005. Sponge Bioactive For Bactericide, Fungicide and Antibiofouling in Coastal Aquaculture. Riset Institute for Coastal Aquaculture, Maros.
Voogd, N. de, Cleary, D. F., Hoeksema, B. W., Noor, A., Soest, R. W. 2006. Sponge Beta Diversity in The Spermonde Archipelago, SW Sulawesi, Indonesia. Marine Ecology Progress Series. 309. 131-142.
Wahyuono, S. 2003. Mencari Obat Antikanker dari Spons Perairan Indonesia, (Online), http://www.pikiranrakyat.com/cetak/0503/
/cakrawala/lainnya02. htm, diakses 18 Februari 2007).
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