Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy

Aussie Fitriani Ghaznawie Bio | Akhtar Fajar Muzakkir | F. Fathlina Bio | Ali Aspar Mappahya | Abdul Hakim Alkatiri | Andi Alfian Zainuddin | Prihantono Prihantono
Article History

Submited : May 9, 2023
Published : August 2, 2023

Introduction: The survival rate of cancer patients was high due to chemotherapy, but it can cause cardiotoxicity and increase morbidity and mortality. Most studies on cancer therapy-related cardiac dysfunction (CTRCD) focus more on the left ventricle. This study assesses chemotherapy's effect on the right ventricle, namely the right ventricle free wall longitudinal strain (RVFWLS). Methods: This study is a prospective cohort conducted from January to December 2022 on thirty-four cancer patients undergoing chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar. The RVFWLS was assessed before and after chemotherapy using echocardiographic. Result: The RVFWLS value after one cycle chemotherapy decreased compared pre-chemotherapy (4.40±4.84; p=0.001). Conclusion: The effect of chemotherapy is a decrease the RVFWLS value after the first cycle of chemotherapy. It should be considered for echocardiographic evaluation, especially the RVFWLS value every cycle of chemotherapy.


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Ghaznawie, A. F., Muzakkir, A. F., Fathlina, F., Mappahya, A. A., Alkatiri, A. H., Zainuddin, A. A., & Prihantono, P. (2023). Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy. Nusantara Medical Science Journal, 8(1), 38-46. https://doi.org/10.20956/nmsj.v8i1.26648


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