VSEIR Mathematical Model on Anthrax Disease Dissemination in Animal Population with Vaccination and Treatment Effect
DOI:
https://doi.org/10.20956/jmsk.v17i1.10050Keywords:
Mathematical model, Vaccination, Reproduction Base Numbers, Equilibrium Point, Routh-Hurwitz Criteria, Treatment.Abstract
Abstract
This research aimed to determine the equilibrium point and analyze the stability of VSEIR model on Anthrax Disease with vaccination and treatment effects. It also aimed at measuring the level sensitivity of Anthrax disease deployment to proportion vaccination effect and proportion treatment effect by using . The writer used qualitative method to achieve the above objectives. The steps were: Reproduction Base Numbers, The R0, was analyzed using stability of disease-free equilibrium points, where the equilibrium point of both is said to asymptotically stable if and unstable if that originally based on the next generation method. Next, the writer also analyze the stability of equilibrium point that was obtained by using the Routh-Hurwitz Criteria and Numeric Simulation. After analyze the sensitivity, the writer finds the proportion of vaccination effects on new-born animal and the treatment of infected animal can reduce the spread of Anthrax Virus and also to terminate the endemic conditions. The numeric simulation is involved to describe the level of vaccination effect new-born animal, and the treatment of infected animal at Anthrax disease deployment.
References
CDC., 2015. Anthrax. Centers for Diseases Control and Prevention [Internet]. [cited 12 February 2017]. Tersedia dari: https://www.cdc.gov/anthrax/basics/how-people-are-infecter.html [15 agustus 2019]
Driessche and Watmough., 2002. Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. Mathematical Biosciences. 180 (2002). hlm. 29–48.
Etbaigha, F., Willms, A.R., and Poljak, Z., 2018 An SEIR model of influenza a virus infection and reinfection within a farrow-to-finish swine farm PLoS ONE 13(9) e0202493. https://doi.org/10.1371/ journal.pone.0202493
Fred, B., &Charlos-Charez, C., 2000. Mathematical Models in Population Biologi and Epidemologi. New York: Springer.
Friedman, A., & Yakubu, A. A., 2013. Anthrax epizootic and migration: Persistence or extinction. Mathematical Biosciences. https://doi.org/10.1016/j.mbs.2012.10.004
Gombe, N. T., Nkomo, B. M., Chadambuka, A., Shambira, G., & Tshimanga, M., 2010. Risk factors for contracting anthrax in Kuwirirana ward, Gokwe North, Zimbabwe. African Health Sciences. Sci. 10:159-64.
Jinhong., 2014. Analysis of an SEIR Epidemic Model with saturated Incidence and Saturated Treatment Function, The Scientific World Journal, Vol.2014:1-11.
Li, J., and Cui., N., 2013 Dynamic Analysis of an SEIR model with distinct incidence for exposed and infectives Scientific World Journal 871393. doi: 10.1155/2013/871393
Murray J.D., 2002, Mathematical Biology: I An Introduction , Third Edition. Springer: New York , USA.
Mushayabasa, S., Marijani, T., & Masocha, M., 2017. Dynamical analysis and control strategies in modeling anthrax. Computational and Applied Mathematics. https://doi.org/10.1007/s40314-015-0297-1
OFFICE INTERNATIONAL DES EPIZOOTIES (OIE)., 2000. Anthrax. In: Manual of Standards Diagnostic and Vaccines, World Health Organization. pp.235-239.
Osman S, Makinde O.D., 2018. Mathematical Modelling of the Transmission Dynamics of Anthrax in Human and Animal Population.
Ruan, S., 2017 Modeling the transmission dynamics and control of rabies in China Math Biosci. 286 65-93. doi: 10.1016/j.mbs.2017.02.005.
Saad-Roy, C. M., van den Driessche, P., & Yakubu, A. A., 2017. A Mathematical Model of Anthrax Transmission in Animal Populations. Bulletin of Mathematical Biology. https://doi.org/10.1007/s11538-016-0238-1
Sun, C., and Hsieh, Y.H., 2010. Global analysis of an SEIR model with varying population size and vaccination Applied Mathematical Modelling 34(10) 2685-2697
Willems, J.L., 1970. Stability theory of dynamical system. London: Thomas Nelson & Sons.
Wiraningsih, E. D.,Agusto, F.,Aryati, L., Lenhart, S., Toaha, S., Widodo and Govaerts, W., 2015. Stability analysis of rabies model with vaccination effect and culling in dogs Applied Mathematical Sciences 9(77) 3805-3817
World Health Organization., 2008. Anthrax in Humans and Animals. 4^th Editon Geneva WHO Press.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Jurnal Matematika, Statistika dan Komputasi is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution License, allowing third parties to copy and redistribute the material in any medium or format, transform, and build upon the material, provided the original work is properly cited and states its license. This license allows authors and readers to use all articles, data sets, graphics and appendices in data mining applications, search engines, web sites, blogs and other platforms by providing appropriate reference.