ANALISIS EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN ANTIHIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK RAWAT INAP DI RSUP Dr. WAHIDIN SUDIROHUSODO
Abstract
Sebagian besar pasien penyakit ginjal stadium akhir (ESRD) yang menyebabkan hemodialisis, dapat mengalami hipertensi. Penelitian ini bertujuan untuk menganalisis efektivitas dan efek samping penggunaan antihipertensi amlodipin tunggal dan kombinasi amlodipin dengan telmisartan, dan kombinasi amlodipin dengan Valsartan pada pasien gagal ginjal kronik selama rawat inap di RSUP Dr. Wahidin Sudirohusodo Makassar. Penelitian ini dilaksanakan di ruangan rekam medik RSUP Wahidin Sudirohusodo selama periode September sampai oktober 2018. penelitian ini merupakan penelitian observasional noneksperimental. pengambilan data dilakukan secara retrospektif. pengambilan data berdasarkan rekam medik pasien gagal ginjal kronik (ESRD) yang mendapat terapi obat antihipertensi amlodipin tunggal, amlodipin kombinasi telmisartan, amlodipin kombinasi valsartan periode Januari sampai Agustus 2018. Dari hasil penelitian dengan melihat persen penurunan dan waktu penurunan tekanan darah pasien dan efek samping maka dapat disimpulkan bahwa Kombinasi amlodipin dan telmisartan paling efektif di antara amlodipin tunggal dan amlodipin kombinasi valsartan dalam menurunkan hipertensi pada pasien gagal ginjal kronik . Efek samping yang ditimbulkan dari kelompok amlodipin dalah adalah udem sebanyak 7,14%, efek samping yang ditimbulkan dari kelompok amlodipin kombinasi Telmisartan adalah hiperkalemia sebanyak 14,28 %, dan efek samping yang ditimbulkan oleh kelompok amlodipin kombinasi valsartan adalah pusing sebanyak 14, 28 %References
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