PENGUJIAN EKSTRAK KELUWAK TERHADAP AKTIVITAS REPRODUKSI DENGAN MODEL Drosophila melanogaster

Authors

  • Nurul Hidayah Base Fakultas Farmasi, Universitas Hasanuddin, Makassar
  • Mufidah Murdifin Fakultas Farmasi, Universitas Hasanuddin, Makassar
  • Firzan Nainu Fakultas Farmasi, Universitas Hasanuddin, Makassar

Abstract

Keluwak merupakan hasil fermentasi secara alami dari biji Pangi (Pangium edule Reinw) yang mengandung senyawa yang bersifat sebagai antioksidan. Senyawa antioksidan dapat mempengaruhi kondisi penuaan sel dalam tubuh dengan cara menangkal radikal bebas penyebab stress oksidatif. Penelitian bertujuan untuk mengetahui efek ekstrak keluwak terhadap aktivitas reproduksi Drosophila melanogaster. Dalam penelitian ini digunakan lalat jantan dan lalat betina yang diberi pakan normal (kontrol sehat), ekstrak keluwak 1,25% dan vitamin C selama 15 hari. Selanjutnya, jumlah total pupa dan jumlah lalat dewasa yang berhasil berkembang dari pupa dihitung setiap tiga hari. Hasil penelitian menunjukkan bahwa ekstrak keluwak 1,25 % dan vitamin C dapat meningkatkan jumlah pupa dan anak dibandingkan dengan kontrol sehat. Dengan demikian dapat disimpulkan bahwa ekstrak etanol keluwak dapat meningkatkan aktivitas reproduksi Drosophila melanogaster

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Published

2019-05-09

Issue

Vol. 23 No. 1 (2019): MFF

Section

Articles

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