KHASIAT MADU MENURUNKAN TEKANAN DARAH DAN HEMATOLOGI PARAMETER
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Abstract
Angka kejadian Diabetes Melitus (DM) terus mengalami peningkatan, baik di dunia, regional, maupun di Indonesia. Salah satu penyebab DM adalah stres oksidatif, sehingga madu sebagai antioksidan alami mampu
menurunkan komplikasi yang terjadi. Penelitian ini bertujuan menilai efek pemberian madu terhadap tekanan darah dan hematologi parameter. Jenis rancangan yang digunakan adalah quasi experiment dengan desain prepost control. Populasi adalah penderita DM tipe 2 di dua wilayah kerja puskesmas di Kota Makassar. Sampel adalah sebagian yang memenuhi kriteria inklusi sebanyak 36 penderita DM tipe 2 yaitu 18 responden kelompok intervensi (KI) (diberikan madu dan edukasi gizi), dan 18 responden kelompok kontrol (KII) (diberikan edukasi gizi). Analisis data menggunakan uji Wilcoxon dan uji Mann-Whitney U. Hasil penelitian yaitu terjadi penurunan signifikan kadar kolesterol total, LDL, Gula Darah Puasa (GDP) dan Tekanan Darah Diastolik (TDD) pada KI. KII terjadi penurunan signifikan pada kadar LDL dan GDP, tetapi terjadi peningkatan signifikan pada TDD. Terjadi perbedaan yang signifikan pada TDD antara KI dengan KII (p=0,04). Pemberian madu memberi perubahan positif
pada GDP (26,2%), total kolesterol (8,3%), LDL (11,7%), HDL (5,4%), tekanan darah sistolik (TDS) (4,1%) dan TDD (9,1%). Kesimpulan dari penelitian bahwa madu menurunkan kadar GDP, kolesterol total, LDL, TDD dan TDS pada penderita DM tipe 2.
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