The aim of this research of flavonoid compounds extract from ethanol Bilajang Bulu (Merremia vitifolia). Empirically, Merremia vitifolia was used by people in Luwu, Southern Sulawesi as a cure for diabetes mellitus injury. The research was supported by previous study, which claimed that Merremia vitifolia had an active compound that worked as anti-virus, insecticides, and anti-bacteres. Methods of this research were through preparation of a Merremia vitifolia leafs sample, maseration, extraction, and flavonoid total assesment by using spectrophotometry UV-Vis. The result obtained that the level of flavonoids was 163,4 mg/L or equivalent to 0,01634%.
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