Asupan Vitamin C dan E Dengan SQ-FFQ terhadap Fungsi Paru Perokok dan Non-Perokok

Siska Rian Pratiwi, Amelia Lorensia, Rivan Virlando Suryadinata

Abstract


Asap rokok merupakan salah satu sumber radikal bebas eksogen yang dapat menyebabkan kerusakan sel yang mengakibatkan penurunan fungsi paru. Vitamin C dan E merupakan antioksidan yang dapat menghambat aktivitas senyawa oksidan. Tujuan dari penelitian ini adalah mengetahui perbedaan kondisi fungsi paru, asupan vitamin C, asupan vitamin E pada perokok aktif dan non perokok, serta pengaruh asupan Vitamin C dan E terhadap kondisi fungsi paru. Desain penelitian yang digunakan adalah case control. Variabel yang diukur meliputi asupan vitamin C dan E dengan semi quantitative-food frequency questionnaire (SQ-FFQ) serta kondisi fungsi paru dengan handheld spirometer. Sampel penelitian ini terdiri dari 63 sampel perokok dan 63 sampel non perokok. Hasil uji menunjukkan fungsi paru pada perokok dan non perokok berbeda signifikan (p=0,00). Asupan vitamin C (p=0,00) dan E (p=0,029) pada perokok aktif dan non perokok juga menunjukkan hasil yang berbeda signifikan.Hasil analisis menunjukkan adanya pengaruh asupan vitamin C (r=0,63) dan vitamin E (r=0,22) terhadap kondisi fungsi paru. Terdapat perbedaan asupan vitamin C,E, dan fungsi paru pada perokok dan non perokok, serta adanya pengaruh asupan vitamin C dan E terhadap fungsi paru.


Keywords


Rokok; fungsi paru; vitamin C; vitamin E

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References


World Health Organization. Global adult tobacco survey: Indonesia report 2011. New Delhi: World Health Organization; 2012.

Kemenkes RI. Riset Kesehatan Dasar 2013. Jakarta: Kementrian Kesehatan RI; 2013.

Lian TY dan Dorotheo U. The Tobacco Control Atlas: ASEAN Region Third Edition 2016. Bangkok: Southeast Asia Tobacco Control Alliance; 2016. 15-33.

Sarma AD, Mallick AR, Ghosh AK. Free Radicals and Their Role in Different Clinical Conditions: An Overview. IJPSR. 2010; 1(3): 185-92.

Gosh M dan Ionita P. Investigation of Free Radicals in Cigarette Mainstream Smoke. MEDIMOND. 2007; 49-55.

Joshi P, Kim WJ, dan Lee S. The effect of dietary antioxidant on the COPD risk : the community-based KoGES ( Ansan – Anseong ) cohort. International Journal of COPD. 2015; (10) 2159-68.

World Health Organization. Report on the Global Tobacco Epidemic, 2011: The MPOWER package. World Health Organization. 2011; 38-73.

Adegoke BO, Akinremi AA, dan Akintobi AE. Effects of Tobacco Smoking on Pulmonary Function Indices Among Undergraduate Students. Nigerian Journal of Medical Rehabilitation. 2015; 18(1):1-14.

Nimse SB dan Pal D. Free Radicals, Natural Antioxidants, and Their Reaction Mechanisms. The Royal Society of Chemistry. 2015; (5) 27986-28006.

Rao SP, Kalva S, Yerramilli A, et al. Free Radicals and Tissue Damage: Role of Antioxidants. Free Radicals and Antioxidants. 2011; 1(4): 1-6.

Lobo V, Patil A, Patak A, Chandra N. Free Radicals, Antioxidants and Functional Foods: Impact on Human Health Pharmacognosy Reviews. 2010; 4(8): 118-126.

Pham-Huy LA, He H dan Pham-Huy. Free Radicals, Antioxidants in Disease and Health. International Journal of Biomedical Science. 2008; 4(2): 89-95.

Polidori MC, Mecocci P, Stahl W dan Sies,H. Cigarette Smoking Cessation Increases Plasma Levels of Several Antioxidant Micronutrients and Improves Resistance Towards Oxidative Challenge. British Journal of Nutrition. 2003; (90): 147–50.

Garcia-Alonso M, Pascual-Teresa S, Santos-Buelga, C and Rivas-Gonzalo JC. Evaluation of the antioxidant properties of fruits. Food Chemistry. 2004; 84(2004): 13-8.

Schunemann H, McCann S, Grant, et al. Lung Function in Relation to Intake of Carotenoids and Other Antioxidant Vitamins in a Population-based Study. American Journal of Epidemiology. 2002; 155(5):463-71.

Burns JS, Dockery DW, Neas L M, et al. Low Dietary Nutrient Intakes and Respiratory Health in Adolescents. Chest Journal. 2007; 6(39): 238-45.

Bentley AR, Kritchevsky SB, Harris TB, et al. Dietary antioxidants and forced expiratory volume in 1s decline: the Health, Aging and Body Composition study. Eur Respir J. 2012; 39(4): 979–84.

Russnes KM, Moller E, Kathryn M. KM, et al. Total antioxidant intake and prostate cancer in the Cancer of the Prostate in Sweden (CAPS) study. A case control study. BMC Cancer. 2006; 16(438):1-12.

Purnasari G, Briawan D, Dwiriani CM. Asupan Kalsium dan Tingkat Kecukupan Kalsium pada Ibu Hamil di Kabupaten Jember. Jurnal MKMI. 2016; 12(4): 261-8.

Tritisari KP, Handayani D, Ariestiningsih AD dan Kusumastuty I. Asupan Makanan Sumber Antioksidan Dan Kadar Glukosa Darah Puasa pada Penderita Dm Tipe 2 di Jawa Timur. Majalah Kesehatan FKUB. 2017; 4(2): 96-04.

Paulose-Ram R, Timothy Tilert T, Dillon C and Brody DC. Cigarette Smoking and Lung Obstruction Among Adults Aged 40–79: United States, 2007–2012. National Health and Nutrition Examination. 2015.

Sharma MD dan Ravi R. Visual Effects of Long Term Active Smoking: Are Aircrew Flying NVG-Aided Missions at a Disadvantage?. Ind J Aerospace Med. 2010; 4(1): 18-5.

Carey MA, Card JW, Voltz JW, et al. It's all about sex: male-female differences in lung development and disease. Trends Endorinol Metab. 2007; 18(8): 308-13.

Johns DP, Walters JAE, Walters EH. Diagnosis and early detection of COPD using spirometry. 2014; 6(11):1557–69.

Ranu H, Wilde M dan Madden B. Pulmonary Function Tests. The Ulster Medical Society. 2011; 80(2):84-90.

Quanjer PH, Pretto JJ, Brazzale DJ dan Boros PW. Grading the severity of airways obstruction: new wine in new bottles. Eur Respir J. 2014; 43: 505–12.

Kementrian Kesehatan RI. Peraturan Menteri Kesehatan RI Nomor 75 Tahun 2003 tentang Angka Kecukupan Gizi yang Dianjurkan Bagi Bangsa Indonesia. Jakarta: Kementrian Kesehatan RI. 2014.

Nawaleh HA, Zead SA, Al-Maghaireh DF. Pulmonary Functiont Test: The value among smoker and nonsmokers. Health Science Journal. 2012; 6(4): 703-13.

Banur A, Dacosta AL, Wiseman MP, Chaudri S. A Study on Effects of Smoking on Spirometry, Thoracic Gas Volume And Residual Volume in Apparently Asymptomatic Smokers. IOSR Journal of Dental and Medical Sciences. 2016; 15(12): 48-54.

Ma J, Hampl JS, Betts NM. Antioxidant intakes and smoking status: data from the continuing survey of food intakes by individuals 1994–1996. Am J Clin Nutr. 2000; 71(3):774-80.

Jain A, Agrawal BK, Varma M, dan Jadhav AA. Antioxidant Status and Smoking Habits: Relationship with Diet. Singapore Med J. 2009; 50(6):624-7.

Tsiligiani IG dan Molen T. A systematic review of the role of vitamin insufficiencies and supplementation in COPD. Respiratory Research. 2010; 11(171): 1-8.

Padayatty SJ, Katz A, Wang Y, et al. Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention. Journal Of The American College Of Nutrition. 2003; 22(1): 18-35.

Jaarin K dan Kamsiah Y. Repeatedly Heated Vegetable Oils and Lipid Peroxidation. Intech. 2012; 211-27.

Yuniati H dan Almasyhuri. Kandungan Vitamin B6, B9, B12 Dan E Beberapa Jenis Daging, Telur, Ikan Dan Udang Laut Di Bogor Dan Sekitarnya. Penel Gizi Makan. 2012; 35(1): 78-89.

Leong XF, Ng CY, Jaarin K dan Mustafa MR. Effects of Repeated Heating of Cooking Oils on Antioxidant Content and Endothelial Function. Austin Journal of Pharmacology and Therapeutics. 2015; 3(2):1-7.




DOI: http://dx.doi.org/10.30597/mkmi.v14i2.3998

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