Potential of Noni Leaf Extract (Morinda citrifolia L.) As Aedes aegypti Mosquito Repellent

Authors

  • Demes Nurmayanti Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia https://orcid.org/0000-0003-1030-6313
  • Lailatul Fithriyah Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia
  • Ngadino Ngadino Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia
  • Irwan Sulistio Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia
  • Slamet Wardoyo Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia
  • Marlik Marlik Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia
  • Mahawiraja Setiawan Department of Environmental Health, Health Polytechnic Jakarta II, Jakarta, Indonesia

DOI:

https://doi.org/10.30597/mkmi.v20i1.27652

Keywords:

Repellent, Noni leaf extract, Aedes aegypti

Abstract

Dengue fever is transmitted every year by the Aedes aegypti mosquitoes in Indonesia. One way to prevent this is by using repellents, such as the noni leaf extract (Morinda citrifolia L.). The objective of this study was to analyze the potential of the noni fruit (Morinda citrifolia L.) leaf extract as a repellent against Aedes aegypti. The study employed a post-test research design with only a control group, using concentrations of 12.5%, 25%, and 37.5%, and 25 mosquitoes with 6 repetitions. The technique for data collection involved counting mosquitoes that perched on hands. The study was conducted from November 2022 to May 2023. Data analysis was performed using SPSS Anova One Away Post Hoc and the power protection formula. The research on Aedes aegypti mosquitoes that perched for 6 hours showed that the noni leaf extract concentration of 37.5% had an average of 2.5 tails perched. The concentration of the noni leaf extract is 37.5%, according to the Pesticide Committee standard (1995). The average protection power for 6 hours is 90.86%. The study also suggests investigating the side effects of use and the addition of an HPMC gelling agent. However, for concentrations of 12.5% and 25%, the protective power is less than 90%. This study shows that concentrations of 37.5% are effective for repelling Aedes aegypti mosquitoes. Further research can be conducted using old or yellowed leaves, as well as for repelling culex and Anopheles mosquitoes.

Author Biographies

Demes Nurmayanti, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Lailatul Fithriyah, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Ngadino Ngadino, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Irwan Sulistio, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Slamet Wardoyo, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Marlik Marlik, Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Department of Environmental Health, Health Polytechnic Surabaya, Surabaya, Indonesia

Mahawiraja Setiawan, Department of Environmental Health, Health Polytechnic Jakarta II, Jakarta, Indonesia

Department of Environmental Health, Health Polytechnic Jakarta II, Jakarta, Indonesia

References

Kemenkes RI. Indonesian Dengue Fever Annual Report 2022. Jakarta: Kementerian Kesehatan Republik Indonesia. 2022. 17–19. https://p2p.kemkes.go.id/wp-content/uploads/2023/06/FINAL_6072023_Layout_DBD-1.pdf

Zeng Z, Zhan J, Chen L, Chen H, Cheng S. Global, Regional, and National Dengue Burden from 1990 to 2017: A Systematic Analysis Based on the Global Burden of Disease Study 2017. EClinicalMedicine. 2021;32:100712. https://doi.org/10.1016/j.eclinm.2020.100712

Kemenkes RI. Indonesia Health Profile 2019. Jakarta: Kementerian Kesehatan Republik Indonesia. 2019.

https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf

Atikasari E, Sulistyorini L. Control of Aedes Aegypti Mosquito Vectors in Surabaya City Hospital. Indonesian Journal of Public Health. 2019;13(1):73. https://doi.org/10.20473/ijph.v13i1.2018.73-84

Zerfu B, Kassa T, Legesse M. Epidemiology, Biology, Pathogenesis, Clinical Manifestations, and Diagnosis of Dengue Virus Infection, and its Trend in Ethiopia: A Comprehensive Literature Review. Tropical Medicine and Health. 2023;51(1). https://doi.org/10.1186/s41182-023-00504-0

Izza BA, Nurmayanti D, Mirasa YA. Spatial Analysis of the Effect of House Index with DHF Cases in Bangilan District, Tuban Regency. BALABA. 2022;18(2):149–158. https://journalkolegium.epidemiologi.id/index.php/kei/article/view/82

Murwanto B, Trigunarso SI, Purwono P. Factors of Social Environment, Physical Environment, and Control of DHF Programme on the Incidence of Dengue Fever (DHF). Jurnal Kesehatan. 2019;10(3):453. http://ejurnal.poltekkes-tjk.ac.id/index.php/JK

Nurmayanti D, Mukarromah HN, Marlik, Ane R La. Geographic Distribution of DHF Cases and Larvae Free Index In Situbondo Regency, 2019-2021. Media Kesehatan Masyarakat Indonesia. 2023;19(1):9–18. https://journal.unhas.ac.id/index.php/mkmi/article/view/22633

Ngadino, Marlik, Nurmayanti D. Resistance of Aedes aegypti Mosquitoes to Cypermethrin. Jurnal Kesehatan Lingkungan Poltekkes Kemenkes Surabaya. 2021. http://repo.poltekkesdepkes-sby.ac.id/3751/

Nurmayanti D. Conventional Detection of Resistance of Aedes aegypti Larvae as DHF Vector in Kediri District Against Temephos. Indian Journal of Forensic Medicine and Toxicology. 2020;14(1):2016–2019.

https://www.academia.edu/108881857/Conventional_Detection_of_Resistance_of_Aedes_aegypti_Larvae_as_DHF_Vector_in_Kediri_District_Against_Temephos

Norris EJ, Coats JR. Current and Future Repellent Technologies: The Potential of Spatial Repellents and Their Place in Mosquito-Borne Disease Control. International Journal of Environmental Research and Public Health. 2017;14(2). https://doi.org/10.3390%2Fijerph14020124

Logan J. An Expert Review of Spatial Repellents for Mosquito Control. Innovative Vector Control Consortium. 2020;(August): 1–72. https://www.ivcc.com/wp-content/uploads/2020/08/An-Expert-Review-of-Spatial-Repellents-for-Mosquito-Control.pdf

Oktari F, Ahyanti M, Yushananta P. Analysis of the Potential of Clove Leaf Extract (Syzygium aromaticum) as a Mosquito Repellent. Ruwa Jurai: Jurnal Kesehatan Lingkungan. 2022;16(2):66–74. http://dx.doi.org/10.26630/rj.v16i2.3490

Putri AV, Hajimi H, Akhmad Z. Effectiveness of Noni Fruit Extract (Morinda citrifolia) as a Vegetable Pesticide for Control of Mice (Mus musculus). Ruwa Jurai: Jurnal Kesehatan Lingkungan. 2021;15(3):144–148.

https://ejurnal.poltekkes-tjk.ac.id/index.php/JKESLING/article/viewFile/3068/1469

Sandra T, Sofro MA, Suhartono S, Martini M, Hadisaputro S. Factors Influencing the Incidence of Dengue Fever in Children Aged 6-12 Years in Tembalang Sub-district Dengue in Children aged 6-12 Years in Tembalang Sub-district. Jurnal Epidemiologi Kesehatan Komunitas. 2019;9(1):28–35. https://dx.doi.org/10.14710/jekk.v4i1.4423

Safe S, Jayaraman A, Chapkin RS, Howard M, Mohankumar K, Shrestha R. Flavonoids: Structure–Function and Mechanisms Of Action and Opportunities for Drug Development. Toxicological Research. 2021;37(2):147–162. https://doi.org/10.1007/s43188-020-00080-z

Paarvanova B, Tacheva B, Savova G, Karabaliev M, Georgieva R. Hemolysis by Saponin Is Accelerated at Hypertonic Conditions. Molecules. 2023;28(20):1–14. https://doi.org/10.3390/molecules28207096

Kurniawan VR, Mutiarawati DT, Endarini LH, Sasongkowati R. Efficacy of Different Betel Leaf Extracts As Repellents Against Aedes Aegypti Mosquito Bites. Manuju: Malahayati Nursing Journal. 2022;4(10): 2564–2572. http://dx.doi.org/10.33024/mnj.v4i10.7511

Ilham R, Lelo A, Harahap U, Widyawati T, Siahaan L. The Effectivity of Ethanolic Extract From Papaya Leaves (Carica papaya L.) as an Alternative Larvacide to Aedes spp. Open Access Macedonian Journal of Medical Sciences. 2019;7(20):3395–3399. https://doi.org/10.3889%2Foamjms.2019.432

Martias I, Simbolon VA. Noni and Papaya Leaf Extracts as Natural Larvicides on Aedes aegypti Mosquito Larvae Mortality. Jurnal Ilmu Kesehatan Masyarakat. 2020;9(01):12–18. https://doi.org/10.33221/jikm.v9i01.820

Pawitri P, Achyani SZ. Effect of Noni Fruit Repellent (Morinda Citrifolia L.) on Aedes Aegypti Mosquito Hispanic Protection Power as a Biology Learning Resource for Senior High School Students. Edubiolock. 2019;1(1):37–49. http://scholar.ummetro.ac.id

Halimah H, Margi Suci D, Wijayanti I. Study of the Potential Use of Noni Leaves (Morinda citrifolia L.) as an Antibacterial Agent for Escherichia coli and Salmonella typhimurium. Jurnal Ilmu Pertania Indonesia. 2019;24(1):58–64.

https://doi.org/10.18343/jipi.24.1.58

WHO. Guidelines For Efficacy Testing Of Mosquito Repellents For Human Skin. Who/Htm/Ntd/Whopes/2009.4. 2009. 1–6. https://www.who.int/publications/i/item/WHO-HTM-NTD-WHOPES-2009.4

Ihwah A, Deoranto P, Wijana S, Dewi IA. Comparative Study Between Federer and Gomez Method For Number of Replication in Complete Randomized Design Using Simulation: Study of Areca Palm (Areca catechu) As Organic Waste for Producing Handicraft Paper. IOP Conference Series: Earth and Environmental Science. 2018;131(1). https://iopscience.iop.org/article/10.1088/1755-1315/131/1/012049/pdf

Overview C. Chapter 2 Basic Tools of Analytical Chemistry. Analytical Chemistry 2.0. 2009. 1–28.

https://resources.saylor.org/wwwresources/archived/site/wp-content/uploads/2012/07/Chapter211.pdf

Chowdhury S, Chakraborty P pratim. How To Choose And Interpret A Statistical Test? An Update For Budding Researchers. Journal of Family and Medicine and Primary Care. 2017;6(2):169–170.

http://www.jfmpc.com/article.asp?issn=2249-4863;year=2017;volume=6;issue=1;spage=169;epage=170;aulast=Faizi

Colucci B, Müller P. Evaluation of Standard Field and Laboratory Methods To Compare Protection Times of The Topical Repellents PMD And DEET. Scientific Reports. 2018;8(1):1–11. https://www.nature.com/articles/s41598-018-30998-2

Khomsatun, Wahyudi, Hari Rudijanto I.W. G. Effectiveness of Betel Leaves Extract (Piper betle, Linn) as Mosquito Anopheles spp Repellent. International Journal of Innovative Research in Science, Engineering and Technology. 2019;8(5):5144–5152. https://doi.org/10.31983/jrk.v2i3.386

Asgarian TS, Moosa-Kazemi SH, Sedaghat MM. Impact of Meteorological Parameters on Mosquito Population Abundance And Distribution In A Former Malaria Endemic Area, Central Iran. Heliyon. 2021;7(12): e08477. https://doi.org/10.1016/j.heliyon.2021.e08477

Reinhold JM, Lazzari CR, Lahondère C. Effects Of The Environmental Temperature on Aedes aegypti and Aedes albopictus mosquitoes: A Review. Insects. 2018;9(4). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316560/pdf/insects-09-00158.pdf

Wahyuni D, Sholikatin N. Repellent Effectiveness Test of Kaffir Lime Leaf Extract (Citrus Hystrix D.C) Against Aedes Aegypti Mosquito. Jurnal Pharma Bhakta. 2022;1(2):20–29. https://jurnalpharmabhakta.iik.ac.id/index.php/jpb/article/view/13/10

Lestari S, Septiyani BN, Proklamasiningsih E. Flavonoid Content and Antioxidant Activity of Kitolod (Hippobroma longiflora L.) at Different Altitude Sri. LenteraBio: Berkala Ilmiah Biology. 2024;13(2):212–218. https://journal.unesa.ac.id/index.php/lenterabio/article/view/23498/10940

Armayanti, Ashari R. Efficiency of Nori Leaf Extract Used As A Spray In The Control of Aedes Aegypti Mosquito. Jurnal Sulolipu: Media Komunikasi Sivitas Akademika dan Masyarakat. 2019;19(2):157–161.

https://journal.poltekkes-mks.ac.id/ojs2/index.php/Sulolipu/article/view/1349/881

Ullah A, Munir S, Badshah SL, Khan N, Ghani L, Poulson BG, et al. Important Flavonoids and Their Role as a Therapeutic Agent. Molecules. 2020;25:1–39. https://doi.org/10.3390/molecules25225243

Luqman BA, Yuliani D, Biologi J, Matematika F, Pengetahuan I, Universitas A, et al. The Effectiveness Extract of Noni Leaf (Morinda citrifolia L.) and Bintaro Leaf (Cerbera odollam) Against Mortality o. LenteraBio: Berkala Ilmiah Biology. 2023;12(2):179–185. https://journal.unesa.ac.id/index.php/lenterabio/index

Wheelwright M, Whittle CR, Riabinina O. Olfactory Systems Across Mosquito Species. Cell and Tissue Research. 2021;383(1):75–90. https://doi.org/10.1007/s00441-020-03407-2

Safitri IA, Cahyati WH. Effectiveness Of Zodia Leaves (Evodia Suaveolens) As Aedes Aegypti Mosquito Repellent. Care Jurnal Ilmu-Ilmu Kesehatan. 2018;6(1):1. https://core.ac.uk/download/pdf/229027773.pdf

Sudiarti M, Ahyanti M, Yushananta P, Tanjungkarang PK. Effectiveness Of Zodia Leaves (Evodia Suaveolens) As Aedes Aegypti Mosquito Repellent. Ruwa Jurai: Jurnal Kesehatan Lingkungan. 2021;15(1):8–15. https://core.ac.uk/download/pdf/229027773.pdf

Pandu ZA, Arif W, Teguh W. Effectiveness of Various Concentrations of Clover Leaf Extract (Syzygium Aromaticum, L.) As A Repellent Against the Rest of the Aedes Aegypti Mosquito. Buletin Keslingmas: Buletin Kesehatan Lingkungan Masyarakat. 2019;38(3):55–62. https://ejournal.poltekkes-smg.ac.id/ojs/index.php/keslingmas/article/view/5399/1413

Sari LR, Hestiningsih R. Repellent Efficacy of Kecombrang (Nicolaia Speciosa Horan) Extract Against Aedes Aegypti Linn Mosquitoes. Jurnal Kesehatan Masyarakat. 2016;3(3):754–763. https://ejournal3.undip.ac.id/index.php/jkm/article/view/12738

Nisa M, Irmayani I, Sarty SD. Development of Spray Gel Formulation for Ethanol Extract of Komba Komba Leaves (Eupatorim Odoratum) as Repellent Candidate. JSFK (Jurnal Sains Farmasi & Klinis). 2022;20;5(1):41–45.

https://openjournal.stifera.ac.id/index.php/jfsi/article/view/93

Downloads

Published

2024-04-04

How to Cite

Nurmayanti, D., Fithriyah, L., Ngadino, N., Sulistio, I., Wardoyo, S., Marlik, M., & Setiawan, M. . (2024). Potential of Noni Leaf Extract (Morinda citrifolia L.) As Aedes aegypti Mosquito Repellent. Media Kesehatan Masyarakat Indonesia, 20(1), 11–19. https://doi.org/10.30597/mkmi.v20i1.27652

Issue

Section

Articles

Deprecated: json_decode(): Passing null to parameter #1 ($json) of type string is deprecated in /home/journal33/public_html/plugins/generic/citations/CitationsPlugin.inc.php on line 49

Most read articles by the same author(s)

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.